| 1 | Hangtown Motocross Classic | Rancho Cordova, California | 2018-05-19 | 450: Eli Tomac, 250: Zach Osborne |
| 2 | Glen Helen Raceway | San Bernardino, California | 2018-05-26 | 450: Eli Tomac, 250: Aaron Plessinger |
| 3 | Thunder Valley Motocross Park | Lakewood, Colorado | 2018-06-02 | 450: Eli Tomac, 250: Jeremy Martin |
| 4 | High Point Raceway | Mount Morris, Pennsylvania | 2018-06-16 | 450: Eli Tomac, 250: Aaron Plessinger |
| 5 | Muddy Creek Raceway | Blountville, Tennessee | 2018-06-23 | 450: Eli Tomac, 250: Shane McElrath |
| 6 | The Wick 338 | Southwick, Massachusetts | 2018-06-30 | 450: Marvin Musquin, 250: Dylan Ferrandis |
| 7 | Red Bud MX | Buchanan, Michigan | 2018-07-07 | 450: Marvin Musquin, 250: Aaron Plessinger |
| 8 | Spring Creek MX Park | Millville, Minnesota | 2018-07-21 | 450: Eli Tomac, 250: Aaron Plessinger |
| 9 | Washougal MX Park | Washougal, Washington | 2018-07-28 | 450: Eli Tomac, 250: Aaron Plessinger |
| 10 | Unadilla MX | Unadilla, New York | 2018-08-11 | 450: Marvin Musquin, 250: Dylan Ferrandis |
| 11 | Budds Creek Motocross Park | Mechanicsville, Maryland | 2018-08-18 | 450: Eli Tomac, 250: R.J. Hampshire |
| 12 | Ironman Raceway | Crawfordsville, Indiana | 2018-08-25 | 450: Justin Barcia, 250: Aaron Plessinger |