| 1 | Hangtown Motocross Classic | Rancho Cordova, California | 2016-05-21 | 450: Ken Roczen, 250: Joey Savatgy |
| 2 | Glen Helen Raceway | San Bernardino, California | 2016-05-28 | 450: Ryan Dungey, 250: Alex Martin |
| 3 | Thunder Valley Motocross Park | Lakewood, Colorado | 2016-06-04 | 450: Ken Roczen, 250: Joey Savatgy |
| 4 | High Point Raceway | Mount Morris, Pennsylvania | 2016-06-18 | 450: Ken Roczen, 250: Joey Savatgy |
| 5 | Muddy Creek Raceway | Blountville, Tennessee | 2016-06-25 | 450: Ken Roczen, 250: Cooper Webb |
| 6 | Red Bud MX | Buchanan, Michigan | 2016-07-02 | 450: Ken Roczen, 250: Cooper Webb |
| 7 | The Wick 338 | Southwick, Massachusetts | 2016-07-09 | 450: Eli Tomac, 250: Cooper Webb |
| 8 | Spring Creek MX Park | Millville, Minnesota | 2016-07-16 | 450: Ken Roczen, 250: Jeremy Martin |
| 9 | Washougal MX Park | Washougal, Washington | 2016-07-23 | 450: Eli Tomac, 250: Alex Martin |
| 10 | Unadilla MX | Unadilla, New York | 2016-08-13 | 450: Ken Roczen, 250: Cooper Webb |
| 11 | Budds Creek Motocross Park | Mechanicsville, Maryland | 2016-08-20 | 450: Ken Roczen, 250: Zach Osborne |
| 12 | Ironman Raceway | Crawfordsville, Indiana | 2016-08-27 | 450: Ken Roczen, 250: Austin Forkner |